Medical and Scientific Consultants
Prof. Aaron Ciechanover
Nobel Prize Winner
PhD, Israeli Biologist and Chemist.
The first Israeli to win a Nobel Prize in the sciences, Dr. Ciechanover is a member of the Israeli Academy of Humanities and Natural Sciences, a foreign member of the US National Academy of Sciences, a foreign member of the Chinese Academy of Sciences, a Distinguished University Professor at The Chinese University of Hong Kong (Shenzhen), President of the Chehanovo Institute of Precision and Regenerative Medicine and Director of the Institute of Chemical and Biomedical Sciences at Nanjing University.
Along with Dr. Avram Hershko and in collaboration with Dr. Irwin A. Rose from the Fox Chase Cancer Center in Philadelphia, Aaron discovered that covalent attachment of ubiquitin to a target protein signals it for degradation. Along the years it has become clear that ubiquitin-mediated proteolysis plays major roles in numerous cellular processes, and aberrations in the system underlie the pathogenetic mechanisms of many diseases, among them certain malignancies and neurodegenerative disorders. Consequently, the system has become an important platform for drug development.
Prof. Eli Keshet
Prof. Eli Keshet, an academician of the Israeli Academy of Sciences, received his Ph.D. in biochemistry in 1975 and then conducted postdoctoral research on retroviral integration and the reverse locus sub-subject under the direction of Nobel Laureate Howard Tymin.
From 1980 to 1981, Eli was a professor of molecular biology in the Department of Developmental Biology and Cancer Research at the Weizmann Institute, where he joined the faculty in 1982. He is a visiting scientist at the National Cancer Institute, the Curie Institute in Paris and Harvard Medical School. He is also an advisor to many major pharmaceutical companies including Roche, Schering-Plough and Novartis and recipient of numerous awards including the E.M.E.T. Prize (awarded by the Prime Minister of Israel), the Rothschild Prize, the TEVA Prize, the Bennett Prize and others.
Prof. Moshe Flugelman
Prof. Moshe Flugelman specializes in interventional cardiology and vascular biology. He is the Director of the Department of Cardiovascular Medicine at the Lady Davis Carmel Medical Center, Haifa, Israel.
He was a visiting Scientist at the National Heart, Lung & Blood Institute of the National Institutes of Health (NIH) in Bethesda, Maryland and was a fellow in experimental angioplasty at Washington Hospital Center. While at the NIH, Prof. Flugelman worked with leading experts in vascular gene therapy.
Prof. Flugelman earned his Medical degree at the Technion – Israel Institute of Technology and completed his cardiology training at the Hadassah Hebrew University Medical Center in Jerusalem.
RunYoung Think Tank Industry Consultants
Prof. Ning Li
Ning Li is currently the Chief Executive Officer at Shanghai Junshi Biosciences. Before he joined Junshi Biosciences, Dr. Li had been appointed as Vice President and Head of Region Asia and China Regulatory Affairs and Medical Policy in Sanofi. He has extensive experience and expertise in clinical research and medical product evaluation.
From 1997 to 2010, Dr. Li worked at US Food and Drug Administration as a regulatory reviewer and held various positions from Oncology drug team reviewer, senior reviewer/expert reviewer, senior GCP medical reviewer to team leader, branch chief with increasing responsibilities. Dr. Li was a member of 8 technical committees and the lead or medical reviewer for more than 30 new drug applications (NDA) and over 200 investigational new drug applications (IND). Prior to his US FDA career, he worked as Sr. study director/Sr. investigator at Westat/NIH Center for Aids clinical trials, and led or participated in 9 phase I/II/III clinical studies. Before that, Dr. Li served on the faculty of Internal Medicine Department at University of Iowa and Shanghai Medical University (Fudan University).
Dr. Li obtained his medical degree from Shanghai Medical University (Fudan University) and a doctorate degree from University of Iowa. He has published more than 30 scientific papers in the area of clinical trial methodology. He is a member of Cooperative Drug Development Grants Review Committee, NIMH, NIH and Special Emphasis Panel NIDR, NIH, an adjunct faculty member at Johns Hopkins University and Peking University, a researcher at Yihong Business School of Shenyang Pharmaceutical University, and an academic advisor at the Pharmaceutical Economics Institute of Sun Yat-sen University. Dr. Li participated in the formulation of multiple FDA/NMPA clinical research technical guidelines.
Prof. Xiang Hu
Professor Hu holds the doctoral degree in biochemistry and molecular biology. He serves as the President of the Cell Research Institute affiliated to the China Medical City, the founder and CEO of Shenzhen Beike Biotechnology Co., Ltd., and the director of Beike Cell Engineering Research Institute. He has won the second prize of the National Technology Invention Awards (for the project “The Key Technology Studies and Clinical Application for Treating Refractory Autoimmune Diseases with Allosome Mesenchymal Stem Cells”). With the support of National Natural Science Foundation of China, Professor Hu has conducted a series of investigation on the pathogenesis and effective treatment of autoimmune diseases, discovered their new pathogenesis and created the new multi-mode treatment method for refractory autoimmune diseases. The allosome mesenchymal stem cell implantation treatment for refractory systematic lupus erythematosus and other autoimmune diseases is the state-of-the-art technology in this field worldwide. His research results have not only enriched the fundamental theories of the pathogenesis but also paved a new path for the treatment of refractory autoimmune diseases. It has demonstrated important scientific values and huge clinical application potentials, and have drawn great attention from his peers at home and abroad.